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DTSTAMP:20220812T074334Z
LOCATION:Rio Room
DTSTART;TZID=Europe/Stockholm:20220627T143000
DTEND;TZID=Europe/Stockholm:20220627T150000
UID:submissions.pasc-conference.org_PASC22_sess121_msa129@linklings.com
SUMMARY:Cellular Blood Flow Modeling with Smoothed Dissipative Particle Dy
 namics
DESCRIPTION:Minisymposium\n\nCellular Blood Flow Modeling with Smoothed Di
 ssipative Particle Dynamics\n\nYe\n\nComputational modeling and simulation
  of cellular blood flow is highly desired for understanding blood microcir
 culation and blood-related diseases such as thrombosis and tumor, but it s
 till remains challenging primarily because blood in microvessels must be d
 escribed as a dense suspension of different types of deformable cells. A s
 moothed dissipative particle dynamics-immersed boundary method (SDPD-IBM) 
 is developed integrating fluid flow and cell behaviors to simulate physiol
 ogical and pathological phenomena involved blood flow. The SDPD is used to
  model the fluid flow, the IBM is used to model the interaction between th
 e fluid and cells, and three cell behaviors are taken into account, deform
 ation, aggregation and adhesion. Simulations are presented for validation 
 studies to show the fidelity of the SDPD-IBM, e.g., the motion of a red bl
 ood cell (RBC) through a constriction, and the computation of the effectiv
 e blood viscosity in tube flow, as well as for several flow configurations
  to demonstrate its potentiality and usefulness, e.g., the motion modes ex
 perienced by a single RBC, the formation and development of thrombosis, an
 d the distribution of RBCs in complex microvascular networks.\n\nDomain: E
 ngineering, Life Sciences
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