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UID:submissions.pasc-conference.org_PASC22_sess134@linklings.com
SUMMARY:MS2E - The Current State of High-Performance Cellular Flow Simulat
 ions: Can We Define a Consistent Vision? (Part II)
DESCRIPTION:Minisymposium\n\nWith the development of large-scale computing
  platforms, cellular flows can now be simulated by taking into account the
  deformations and interactions of individual cells. The continuous increas
 e in computational capacity enabled high-fidelity flow simulations employi
 ng detailed cell models to become a valuable complement to experimental st
 udies, giving access to more details and aiding in the design of microflui
 dic setups. Some of these developments happen in competition, and some ind
 ividually, around a diverse set of scientific questions. However, the func
 tionality overlap, the limits, and the differences of the proposed methods
  are not necessarily clear. This minisymposium aims to benefit our communi
 ty by setting the following goals: 1) to connect the prominent members of 
 the current bleeding edge research in cellular flow simulations and displa
 y the state of the art of these simulations 2) to provide a platform for a
 n open forum directed discussion after the presentations to deliberate on 
 the current limitations, necessary validations, overlaps and unique featur
 es in functionality, and upcoming targets in the development of these code
 s.\n\nCell Cluster Modelling for Computational Analysis of Cluster Metasta
 tic Potential\n\nCimrak, Bohinikova, Jancigova, Mulik\n\nNumerous studies 
 suggest that clusters of circulating tumour cells have higher metastatic p
 otential than that of single cells. Common agreement was that this is ball
 anced by their short life time due to their disintegration after passing m
 icrocapillaries. Recent study (M.R.King et al., doi: 10.1152/...\n\n------
 ---------------\nCharacterisation of Cellular Properties and Dynamics in M
 icrofluidics\n\nZhang, Chien, Gompper, Fedosov\n\nSorting cells based on t
 heir intrinsic properties is highly desirable, since changes in cell defor
 mability are often associated with various stress conditions and diseases.
  Deterministic lateral displacement (DLD) devices offer high precision for
  rigid spherical particles, while their success in sor...\n\n-------------
 --------\nLinking Physics and Biology in Simulations of Vascular Networks\
 n\nKrüger, Enjalbert, Zhou, Hardman, Bernabeu\n\nThere has been a recent i
 ncrease in modelling of blood flow in disease, such as malaria, sickle cel
 l anaemia or cancer. Blood flow modelling becomes particularly challenging
  at the scale of arterioles and capillaries where the diameters of blood v
 essels and red blood cells (RBCs) are similar. In the...\n\n--------------
 -------\nLong-Time Mesoscopic Simulation of Microvascular Blood Flow in Ze
 brafish Enabled by a Multiscale Parallel-in-Time Method\n\nLi, Yin, Hasega
 wa, Karniadakis\n\nThe intrinsic stochastic effects can play an important 
 role in mesoscopic processes, while the time step allowed in a mesoscopic 
 simulation is restricted by rapid cellular/subcellular dynamic processes, 
 which limits the timescale of mesoscopic simulations. To break this bottle
 neck and achieve a biol...\n\n\nDomain: Engineering, Life Sciences
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