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DTSTAMP:20220812T074334Z
LOCATION:Rio Room
DTSTART;TZID=Europe/Stockholm:20220627T160000
DTEND;TZID=Europe/Stockholm:20220627T163000
UID:submissions.pasc-conference.org_PASC22_sess134_msa156@linklings.com
SUMMARY:Linking Physics and Biology in Simulations of Vascular Networks
DESCRIPTION:Minisymposium\n\nLinking Physics and Biology in Simulations of
  Vascular Networks\n\nKrüger, Enjalbert, Zhou, Hardman, Bernabeu\n\nThere 
 has been a recent increase in modelling of blood flow in disease, such as 
 malaria, sickle cell anaemia or cancer. Blood flow modelling becomes parti
 cularly challenging at the scale of arterioles and capillaries where the d
 iameters of blood vessels and red blood cells (RBCs) are similar. In these
  cases, computationally expensive cell-based models are still required to 
 uncover suspension flow effects and predict cell distribution and tissue o
 xygenation. Deformable RBCs are typically modelled as hyperelastic or visc
 oelastic capsule-vesicle hybrids that are fully coupled to the ambient flu
 id flow and allow to capture the cell deformation and dynamics on the micr
 on level. In order to enable more quantitative predictions in larger blood
  vessel networks (e.g. on the organ level), more efficient reduced models 
 are required. I will give a short overview of existing microscopic blood f
 low models and ongoing activities to develop effective blood flow models a
 pplicable to larger scales.\n\nDomain: Engineering, Life Sciences
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