Tissue Growth in Free or Confined Environments: a Comparison Between Experiments and Numerical Simulations
Presenter
DescriptionWe developed PalaCell2D, a numerical framework to model tissue growth. It is based on the dynamics of interacting cells described by their contour, deformability, proliferation rate and contact with neighbors. We simulate such a tissue in different situations and compare the behavior with the corresponding in-vitro experiments. In particular we first consider a growing tissue in a capsule and the proliferation rate as a function of the mechanical pressure. Second, we simulate a front of cells laterally confined within two walls and its movement due to proliferation and cell motility. A good agreement is found between experiments and simulations.
TimeTuesday, June 2816:30 - 17:00 CEST
LocationRio Room
Event Type
Minisymposium
Computer Science and Applied Mathematics
Life Sciences
Physics